![]() Since the inception of the NCAA women's tournament in 1982, Mulkey has been involved in that tournament as a player or coach every year except 19. This made her the first woman to have won NCAA Division I basketball titles as a player and a head coach, and only the fourth person (after Joe B. The rise of the Baylor program under Mulkey was capped off in 2005 with a national title when the Bears defeated Michigan State in the championship game at Indianapolis. They have won at least 20 games every year, and only once has the team lost more than 10 games in a season. In her first season at Baylor, she led the Lady Bears program to its first NCAA tournament bid the Lady Bears have gone to postseason play every year since Mulkey's arrival. In 2000, Mulkey took over a Baylor program that had finished the 1999–2000 season 7–20 and last in the Big 12 Conference, and had never received an invite to the NCAA tournament. JSTOR ( November 2021) ( Learn how and when to remove this template message).Unsourced material may be challenged and removed. Please help improve this article by adding citations to reliable sources. This section needs additional citations for verification. The team won all six games to claim the gold medal. She continued with the national team to represent the US at the 1984 Olympics. The team easily beat each of the eight teams they played, winning by an average of just under 50 points per game. In 1984, the USA sent its National team to the 1984 William Jones Cup competition in Taipei, Taiwan, for pre-Olympic practice. The Soviets Elena Chausova received the inbounds pass and hit the game winning shot in the final seconds, giving the USSR team the gold medal with a score of 84–82. This game was also close, and was tied at 82 points each with six seconds to go in the game. The USA team won their next four games, setting up the gold medal game against USSR. In an opening round game, the USA team had a nine-point lead at halftime, but the Soviets came back to take the lead, and a final shot by the USA failed to drop, leaving the USSR team with a one-point victory 85–84. The team won six games, but lost two against the Soviet Union. Mulkey played for the USA National team in the 1983 World Championships, held in Sao Paulo, Brazil. The team won all five games to earn the gold medal for the event. Mulkey was selected to be a member of the team representing the US at the 1983 Pan American Games held in Caracas, Venezuela. Mulkey and the Lady Techsters won the 1988 NCAA Championship. During her 15-year tenure as assistant and associate head coach under Leon Barmore, Louisiana Tech posted a 430–68 record and advanced to seven Final Fours. She became an assistant at Tech in 1985 and was promoted to associate head coach in 1996. The 5 ft 4 in (1.63 m) Mulkey was an All-American point guard at Louisiana Tech University, winning two national championships as a player-the AIAW title in 1981 and the inaugural NCAA title in 1982-and in 1984 was the inaugural winner of the women's version of the Frances Pomeroy Naismith Award, given to the nation's top college senior under 5'6"/1.68 m (the height limit was later raised to 5'8"/1.73 m). She later achieved high academic honors as an inductee into the College Sports Information Directors of America Academic Hall of Fame for her classroom achievements at Louisiana Tech. As high school valedictorian, she posted a perfect 4.0 GPA. After playing basketball at Nesom Junior High School in Tickfaw, Louisiana, she led her Hammond High School basketball team to four consecutive state championships. Kim Mulkey was one of the first girls in the US to play organized basketball with boys. Mulkey was inducted into the Women's Basketball Hall of Fame in 2020 and was also inducted into the Naismith Memorial Basketball Hall of Fame. She won three NCAA championships as the coach of Baylor in 2005, 2012, and 2019. A Pan-American gold medalist in 1983 and Olympic gold medalist in 1984, she became the first person in NCAA women's basketball history to win a national championship as a player, assistant coach, and head coach. She is the head coach for Louisiana State University's women's basketball team. Kimberly Duane Mulkey (born May 17, 1962) is an American college basketball player and coach.
0 Comments
![]() Likewise our COBIT ® certificates show your understanding and ability to implement the leading global framework for enterprise governance of information and technology (EGIT). Take advantage of our CSX ® cybersecurity certificates to prove your cybersecurity know-how and the specific skills you need for many technical roles. Whether you are in or looking to land an entry-level position, an experienced IT practitioner or manager, or at the top of your field, ISACA ® offers the credentials to prove you have what it takes to excel in your current and future roles. Get an early start on your career journey as an ISACA student member. Start your career among a talented community of professionals. We are all of you! Meet some of the members around the world who make ISACA, well, ISACA.Ĭontribute to advancing the IS/IT profession as an ISACA member. ISACA membership offers these and many more ways to help you all career long. Participate in ISACA chapter and online groups to gain new insight and expand your professional influence. Members can also earn up to 72 or more FREE CPE credit hours each year toward advancing your expertise and maintaining your certifications.Īs an ISACA member, you have access to a network of dynamic information systems professionals near at hand through our more than 200 local chapters, and around the world through our over 165,000-strong global membership community. ISACA ® membership offers you FREE or discounted access to new knowledge, tools and training. Gain a competitive edge as an active informed professional in information systems, cybersecurity and business. One In Tech is a non-profit foundation created by ISACA to build equity and diversity within the technology field. Information and technology power today’s advances, and ISACA empowers IS/IT professionals and enterprises. ISACA is, and will continue to be, ready to serve you.īenefit from transformative products, services and knowledge designed for individuals and enterprises. We serve over 165,000 members and enterprises in over 188 countries and awarded over 200,000 globally recognized certifications. ![]() Today, we also help build the skills of cybersecurity professionals promote effective governance of information and technology through our enterprise governance framework, COBIT ® and help organizations evaluate and improve performance through ISACA’s CMMI ®. Our community of professionals is committed to lifetime learning, career progression and sharing expertise for the benefit of individuals and organizations around the globe. For 50 years and counting, ISACA ® has been helping information systems governance, control, risk, security, audit/assurance and business and cybersecurity professionals, and enterprises succeed. For example, on a roller coaster high positive g is experienced when the car's path curves upwards, where riders feel as if they weigh more than usual. Roller coasters are usually designed not to exceed 3 g, although a few notable exceptions produce as much as 6.7 g. A typical cough produces a momentary g-force of 3.5 g, while a sneeze results in about 2 g of acceleration. In everyday life, humans experience g-forces stronger than 1 g. ![]() Usually, accelerations beyond 100 g, even if momentary, are fatal. In rocket sled experiments designed to test the effects of high acceleration on the human body, Colonel John Stapp in 1954 experienced 46.2 g for several seconds. In addition, some illnesses, particularly cardiovascular problems, reduce g-tolerance. To some degree, g-tolerance can be trainable, and there is also considerable variation in innate ability between individuals. Race car drivers have survived instantaneous accelerations of up to 214 g during accidents. There is considerable variation among individuals when it comes to g-force tolerance, however. However, sustained g-forces above about 16 g for a minute can be deadly or lead to permanent injury. Humans can tolerate localized g-forces in the 100s of g's for a split second, such a hard slap on the face may impose hundreds of g locally but not produce any real damage. The symbol g is properly written both lowercase and italic to distinguish it from the symbol G, the gravitational constant and g, the symbol for gram, a unit of mass, which is not italicized.Īnalysis of g-forces are important in a variety of scientific and engineering fields, especially planetary science, astrophysics, rocket science, and the engineering of various machines such as fighter jets, race cars, and large engines. The g is a non-SI unit equal to the nominal acceleration of gravity on Earth at sea level (standard gravity), which is defined as 9.80665 m/s2 (32.174 ft/s2). G-force is not an absolute measurement of force and the term is considered a misnomer by some. It is proportional to the reaction force that an object experiences as a result of this acceleration or, more correctly, as a result of the net effect of this acceleration and the acceleration imparted by natural gravity. G force is a measurement of an object's acceleration expressed in g-s. Drivers experience severe g-forces as they corner, accelerate and brake. A physical force equivalent to one unit of gravity that is multiplied during rapid changes of direction or velocity. ![]() This review focuses on the current understanding of the mechanism of action of rituximab and suggests ways to improve its clinical efficacy. A better understanding of rituximab-induced cell killing will allow the development of new, more effective antibodies derived from rituximab as well as innovative treatment modalities designed to optimize its mechanisms of action through selection of the most sensitive tumors, potentiation of cytotoxicity mechanisms or neutralization of resistance, design of optimal dosing schedules, and finding the best synergies. ![]() Several recent studies on CD20 structure and downstream signaling pathways have put forward key arguments that have helped to elucidate the in vivo mechanisms of action of rituximab. It is therefore difficult to evaluate the respective contribution of each of these effects that, moreover, could have different contributions according to lymphoma subtype. Most of these studies were performed with CD20 + cell lines in vitro and in murine models and in some cases with fresh neoplastic B cells in vitro. Other studies have suggested that rituximab may have a “vaccinal” effect. In vitro data suggest that it induces apoptosis, complement-mediated lysis (complement-dependent cytotoxicity ), and antibody-dependent cellular cytotoxicity (ADCC) and some studies seem to confirm the involvement of these mechanisms in vivo. Rituximab has become the hallmark of anticancer mAbs, which offer a new approach to the treatment of B-cell lymphoproliferative disorders.Īlthough the clinical effectiveness of rituximab is no longer in question, its in vivo mechanisms of action have yet to be elucidated. Rituximab has some therapeutic activity in antibody-based autoimmune diseases, 2 and its indications are likely to be extended in the next few years. It is the first approved targeted treatment in the field of oncology and its impact on the treatment of NHL is evidenced by the short interval between its initial description 1 and its approval by both American and European authorities (19, respectively). 1 Rituximab is currently indicated in both follicular and aggressive B-cell non-Hodgkin lymphomas (NHL). ![]() Rituximab was created by fusing the light- and heavy-chain variable domains of 2B8, a murine monoclonal anti-CD20 antibody and human κ light-chain and γ1 heavy-chain constant regions. It binds specifically to CD20, an antigen expressed by most human B lymphocytes. Rituximab is a chimeric monoclonal antibody (mAb) produced by recombinant technology. A better understanding of how rituximab acts in vivo should make it possible to develop new and more effective therapeutic strategies. Here, we review the current understanding of the mechanism of action of rituximab and discuss approaches that could increase its clinical activity. Rituximab also has a delayed therapeutic effect as well as a potential “vaccinal” effect. Rituximab has been shown to induce apoptosis, complement-mediated lysis, and antibody-dependent cellular cytotoxicity in vitro, and some evidence points toward an involvement of these mechanisms in vivo. Despite its demonstrated clinical effectiveness, its in vivo mechanisms of action remain unknown and could differ by subtype of lymphoma. Rituximab is currently used in the treatment of both follicular and aggressive B-cell non-Hodgkin lymphomas. Rituximab (MabThera, Rituxan) is a chimeric IgG1 monoclonal antibody that specifically targets the CD20 surface antigen expressed on normal and neoplastic B-lymphoid cells. ![]() Behind the wheel of the TRX®, with its 523kW (702hp) Supercharged 6.2L HEMI V8 engine, there’s only one place you´ll always be…in the lead. Wherever the RAM TRX® leads, the crowd follows. Heated and Ventilated Front and Rear Outer Seats (4 positions).Premium 900-watt Harman Kardon® Premium Sound System.12” Touchscreen Uconnect® with Reconfigurable Split-screen Functionality, Navigation, and Performance Pages.Carbon Fiber Interior Accents, Partial Premium Leather and Suede Trim.SRT® signature Flat Bottom Steering Wheel with Paddle Shifters for the first time on a Ram.Console-mounted Performance Floor Shifter.Powder-coated Bumpers with new Rear Tow Hooks & Front Skid Plate.Massive Performance Hood with Functional Air Intake & Twin Heavy Duty Air Filters.Robust 35-inch Goodyear® Wrangler® Territory Tyres for superior control and stability in shifting conditions.Design elements shared with the toughest, most rugged desert-racing trophy trucks.Tuned for ultimate off-roading Wider Track, Exclusive Bilstein® Black Hawk® e2 Performance Shocks, 295mm Ground Clearance.Launch Control with Launch Assist + 8 different Drive Modes.Segment-leading 6.2L Supercharged HEMI® V8.It’s no surprise that as world’s quickest and most powerful pickup truck, the RAM 1500 TRX ® takes its throne at the apex of New Zealand’s best range of full-size pickup trucks. Segment disrupting style, luxury, capability, technology, and the performance that only other trucks dream of. And wait till you hear what it sounds like….įor the first time ever, RAM has defied convention by delivering a pickup truck that has it all…. With its beastly Supercharged V8 powerhouse, massive suspension travel & tuned exhaust, it delivers the power and performance that only other trucks dream of. ![]() ![]() The 6.2-liter supercharged HEMI ® V8 engine sets new benchmarks for power and performance in this category and the long list of performance-ready features, high-end materials and high-tech features have never been seen before.īuilt off America’s most awarded light-duty pickup truck, the RAM 1500 platform, the RAM TRX ® is built to rule the road. When the pedal hits the metal, the fight between chest and seatback will be happily lost. Engineered to handle the most punishing conditions with extreme capability and to outperform every other truck the RAM 1500 TRX ® is the apex predator of the pickup truck world.įor the few that will climb up and take the wheel, they’ll need to rev-match their heartbeat to the monster under the hood. Whilst the announcement video suggests that the series was cancelled because of the ongoing public health and social issues in America, a definitive reason was not given. “It was a whirlwind of experiences and a masterclass in how to tell stories and represent people and represent big issues around the world.” – Johnny Harris, via YouTube. After leaving the company, he continued his work on his personal YouTube channel, creating long-form videos about. This is devastating news for the millions of viewers like myself who loved the series for what it was an educational, stylish and well-presented documentary series that broadened your horizons whilst keeping you entertained. Release Calendar Browse Movies by Genre Top Box Office Showtimes & Tickets Movie News India Movie Spotlight. Johnny Harris, creator and star of Vox Borders, announced yesterday (September 14 th) on his YouTube channel that the series and season 5 ‘Vox Borders USA’ has been cancelled. Top 250 Movies Most Popular Movies Top 250 TV Shows Most Popular TV Shows Most Popular Video Games Most Popular Music Videos Most Popular Podcasts. (Excluding a few from SoundCloud, see the spreadsheet. Yes, according to the creator of the series Johnny Harris, Vox Borders has been cancelled and season 5 will not air. A collection of all of the background music used in the popular video series Vox Borders: Hong Kong.6K loves, 1. ![]() GROWING BELUSHI: Has the cannabis series been smoked by Discovery? 8.4M views, 9.9K likes, 4.6K loves, 1.7K comments, 57K shares, Facebook Watch Videos from Vox Borders: Cumbia. When Vox launched a dedicated YouTube program seven years ago, it was a team of two, aiming to create a new type of explainer video for the internet. ![]() Unfortunately, fans of the series have been left devastated by news that this particular border has recently been shut by Vox. House Speaker Kevin McCarthy visits U.S.-Mexico border By Claudia Grisales Published Februat 5:26 PM EST Listen 4:01 With southern Arizona as his backdrop, House Speaker Kevin. ![]() She really belts it out like she is a contestant on a television singing competition or something. Best of luck to you! We Are Not on The Voiceĭear Miss Open Office Manners: I have a coworker who bursts into song loudly throughout the day. If it doesn’t, I’m afraid to say, you will need to go to your boss because it is an HR issue at that point. What’s up?” He might admit it or he might not, but either way, you put him on notice that you are going to call him out on his behavior, which should stop him right there. The next time he stares at you during a meeting, go right up to him afterwards, look him in the eye, and say, “I couldn’t help but notice you were staring at me during the meeting. I don’t want to go to my boss about this as I feel like a child telling the teacher, “He’s looking at me!” What can I do to make him stop?ĭear I Know I’m Good Looking: I have a solution for you that has worked for me in the past. Not only does he do it while I am at a workstation, he also stares at me during meetings. Read on! Stop Looking at Me!ĭear Miss Open Office Manners: I am a woman who works in an open office with a man who is always staring at me. In this installment, I discuss coworkers who stare, ones who think they are the next American Idol, and ones who strengthen their core at their desk. Why do some people find it so hard to be polite in the workplace? Is it because you are around your coworkers so much that you start feeling comfortable? And in some people’s cases, a little too comfortable? Just a thought…anyway, it’s time for some more friendly reminders from Miss Open Office Manners. ![]() Without using any third party software, MacX MediaTrans has an inbuilt Auto compression tool that automatically compresses large 4K, Movies, HD video files to save iPhone space.You can transfer videos in MKV, FLV, AVI, WMV and more besides the regular ones that are accepted by iTunes – another iTunes limitation superseded.With MacX MediaTrans, you can transfer ONLY essential files selectively from iPhone to Mac without wasting time to sync all the files, especially the unnecessary ones as it is for iTunes. If you have used iTunes, you know that you must first sync your iPhone such that all your files are synced at once. ![]() All your files including photos, music, videos, eBooks, iTunes U, apps between iOS and Mac can be transferred back and forth, without any limits. You can back up data from your iPhone X/8/7/6s or later to MacBook Pro/Air and BACK, making it a two-way sync software.Fix your iTunes errors with MacX MediaTrans. MacX MediaTrans is stable in operation and has no iTunes errors. If you have used iTunes, you know it usually has errors.With MacX MediaTrans, you can selectively backup individual folders of your choice, for example iPhone photos from Camera roll, Podcasts, Photo Library, TV Shows, iTunes U, Movies and any other folder of your choice as shown below – which is different for iTunes where you must backup everything at once (even the unnecessary files).As compared to other iPhone X/8/7/6s or later transfer options, it is 5 × faster and an added advantage is that it is user friendly, and so easy to operate. MacX MediaTrans has the fastest file transfer speed.Here are some of the reasons you MUST consider MacX MediaTrans as an iTunes alternative. It is a robust software that gives the user freedom over his iPhone device without any limitation, a very suitable iTunes alternative. MacX MediaTrans is a FREE and Quick Transfer option to Backup iPhone X/8/7/6s data and free up iPhone space. Transfer files from iPhone to Macbook or PC without iTunes (Best iTunes alternative) You could google your way through the Best iTunes alternatives to enable easy transfer of files from your iPhone to iMac or MacBook BUT there is no better option than MacX MediaTrans. In case you sync your iPhone to MacBook pro/Air or iMac with iTunes, any file erased from the iPhone shall also be erased on the MacBook.To access your music from your iPhone through iTunes, you have to authorize your MacBook Air/Pro, BUT yet each apple ID can allow up to 5 computers.You need an iTunes alternative, and here are some of the many known limitations iTunes has as a Media Transfer option. Best iTunes Alternative to Backup all your files It also allows you to replace the OpenDNS logo with your own logo or image.įor example in the screenshot below, I replaced the logo with my own display picture (for testing purpose I blocked Advance settings You could decide the look and message any user gets after he visits a guide page, block page or phishing block page. You may also block internal IP addresses. It provides malware and botnet protection as well as phishing protection. Here you can add an extra layer of security to your computer. Move on to “Security” link given on the left. And don’t forget to select “Always block” or “Never block” from the drop down. Just enter the domain name in the box given at the bottom and press add domain. You can block or allow any domain of your choice. I could increase the filter level to apply more restrictions.Īlso there is an option to manage individual domain. ![]() If we choose “Low” filtering level then all the porn sites will be blocked by OpenDNS. Here I got several options to choose my filtering level.īy default, nothing is blocked. For example I clicked on Web content filtering link on the left. When you click on them, it will open the corresponding settings panel on the right. Web Content FilteringĪs you can see the screenshot given below, there are various links on the left pane. Click on Add this network button given below your IP address.Īfter adding the IP address, select your network by clicking on the drop down. It will automatically detect your IP address. Click on the link and it will redirect you to dashboard settings. You’ll get a confirmation link in your mailbox. To utilize all its features, all you need to do is signup with them. When you look for a website, it immediately finds the corresponding IP address and hence gets it to load faster. OpenDNS servers have a huge collection IP addresses of millions of web pages. Go to Control Panel-> Network And Internet-> Network and Sharing System-> Local Area Connection-> Internet Protocol Version 4 (TCP/IPv4). You need to replace your old DNS server IPs with the following. Only thing you have to do is open your network connection settings and replace the preferred and alternate DNS server with OpenDNS servers. No, you don’t need any software to install. OpenDNS is a free DNS service that can not only speed up your internet but also provide you options like web content filtering, anti-phishing, malware protection, smart cache and much more. ![]() Now, if the DNS server that’s used by your ISP (internet service provider) is slow, then it will take more time to resolve the domain name thereby increasing the overall time taken by a website to load. These numbers are DNS server addresses (202.144.66.6, 202.144.13.50 in the screenshot given below). If you check the Local Area Connection settings in Network and sharing centre of your Windows PC, you’ll find numbers inside Preferred DNS server and Alternate DNS server. The role of a DNS server is to tell the computer that is equivalent to the IP address 74.125.43.99 and hence it could retrieve the information for that site. Your computer doesn’t understand the word Google. Similarly, you could open other websites by typing their IP addresses (if you know them that is). For example, if you type in your browser address bar then Google would open up. You can open any domain name by entering its IP address in the browser’s address bar.īut human mind can’t remember IP addresses and hence we’ve got domain names or what we can call a website address. ![]() When it’s time to see whether you can actually put anything into space without it exploding, the game shifts to Mission Control mode. Combine this with how equipment reliability increases each season, and it’s decision time: do you push now and hope to get lucky and not kill anyone, or do you ensure mission success, which gets you prestige and money, but risk seeing you competitor’s rocket soar through the sky while you sit on Earth sipping drinks Mad Men style? Add the need to repeatedly upgrade your spaceport facilities to hire more staff, and the game gets pleasantly hectic. However, and here’s the fun part, you can skip most of the mission steps, but if you skip one to save time and money, you’ll increase the possibility of the next mission step failing. There are many choices to make as you are trying to coordinate numerous space programs each with a number of mission configurations (smaller development steps). As the Director, you’ll constantly have to decide which programs to open and when to send your staff and astronauts for training. Now, this wouldn’t be a management game if you didn’t have to deal with planning the component development and staff training for maximum efficiency in minimum time. By the time the X-15 has safely landed back to earth, you’ll have opened various space programs, hired technical personnel to work either in R&D or at your shiny new Mission Control Center, and hired astronauts and cosmonauts willing to risk their lives to see their house from space. The game starts you off with a lengthy, but quite necessary, tutorial in which Buzz leads you from constructing the first Mission Control Center to launching the X-15, the world’s first operational spaceplane. All these modes come in three difficulty settings. In addition to the campaigns, there’s a sandbox mode for each agency that offers a more open-ended experience. The GSA campaign is, instead, a race against bureaucrats as it’s all about meeting short-term goals set by the government. If you pick either of the first two, then you are racing for the Moon. You can play a campaign as NASA, the SSA, or GSA. There’s quite a bit of content in SPM that more than justifies the game’s $9.99 price tag. The good thing is that you can turn the music down in-game and, instead, enjoy your choice of period-appropriate tunes. The text can also get tiring as it’s rather small and often hard to read.The music isn’t great either, with one theme for each agency playing on a loop. This would be fine if you didn’t have to go through most of those menus and submenus on every single turn, making their sameness painfully apparent. While the menus are well-organized, they all look a bit too similar. The UI consists mostly of a series of menus, submenus, and submenus of submenus. Visually, the game isn’t the prettiest, as some members of the forum have also pointed out, but I find the graphics adequate for a game of this genre. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |